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Name must be less than 100 characters Concern that a highly pathogenic virus might cause the next influenza pandemic has spurred recent research into influenza and its complications. 2013 Nov;7 Suppl 3(Suppl 3):24-35. doi: 10.1111/irv.12174.Mycopathologia. Epub 2018 Oct 23.Influenza Other Respir Viruses.
This co-pathogenesis is characterized by complex interactions between co-infecting pathogens and the host, leading to the disruption of physical barriers, dysregulation of immune responses and delays in a return to homeostasis. 2020 Jul 7;11(4):e00975-20. Influenza: pathogenesis and host defense. Copyright © 2001 John Wiley & Sons, Ltd.Please check your email for instructions on resetting your password. Pathogenesis of influenza in humans When influenza virus is introduced into the respiratory tract, by aerosol or by contact with saliva or other respiratory secretions from an infected individual, it attaches to and replicates in epithelial cells. 2020 Jul 20;20(1):214. doi: 10.1186/s12866-020-01890-9.Pharo EA, Williams SM, Boyd V, Sundaramoorthy V, Durr PA, Baker ML.Viruses.
doi: 10.1128/mBio.00975-20. Nature Publishing Group
This site needs JavaScript to work properly. Epub 2015 Mar 5.Jeannoël M, Lina G, Rasigade JP, Lina B, Morfin F, Casalegno JS.Eur J Clin Microbiol Infect Dis. 2009 Oct 30;10(1):102. doi: 10.1186/1465-9921-10-102.Am J Pathol.
Our understanding of the host defense and pathogenesis of influenza has come from parallel studies in animal models and humans.
Due to the scourge of H. influenzae type b (Hib) disease, the rise in the number of antibiotic‐resistant Hib strains isolated, and the limited number of behavior modifiers available to curb Hib disease, a great amount of effort was put into the development of an effective Hib vaccine. Whereas lung virus titers were similar between the sexes, females … Online ahead of print.Cell Rep. 2020 Jul 21;32(3):107915. doi: 10.1016/j.celrep.2020.107915. The rapid evolution of influenza A and B viruses contributes to annual influenza epidemics in humans.
Herfst S, van den Brand JM, Schrauwen EJ, de Wit E, Munster VJ, van Amerongen G, Linster M, Zaaraoui F, van Ijcken WF, Rimmelzwaan GF, Osterhaus AD, Fouchier RA, Andeweg AC, Kuiken T.Vet Pathol.
Die Spezies Influenza-B-Virus (FLUB) wird nach dem Ort des Auftretens in mehrere Stamm-Linien eingeteilt, z. The influenza viruses are some of the most important human pathogens, causing substantial seasonal and pandemic morbidity and mortality.
Epub 2015 Mar 5.Am J Physiol Lung Cell Mol Physiol. Nat Rev Microbiol.
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Author information: (1)Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, Gainesville, FL 32608-1197.
2020 Jun 12;11:1293. doi: 10.3389/fmicb.2020.01293. C. Pathogenesis.
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Bacterial superinfection in the lungs of people suffering from influenza is a key element that promotes severe disease and mortality. The virus replicates in cells of both the upper and lower respiratory tract. Epub 2020 Jul 3.Goncheva MI, Conceicao C, Tuffs SW, Lee HM, Quigg-Nicol M, Bennet I, Sargison F, Pickering AC, Hussain S, Gill AC, Dutia BM, Digard P, Fitzgerald JR.mBio.
eCollection 2020 Sep.J Infect Public Health. In this Review, advances in our understanding of the underlying mechanisms are discussed, and the key questions that will drive the field forwards are articulated.
Bender BS(1), Small PA Jr.
2014 Jul;88(14):8166-79. doi: 10.1128/JVI.00270-14. Binding of host proteases by the viral neuraminidase to assist activation of the haemagglutinin, shortening of the neuraminidase and substitutions in the polymerase gene, PB2, have all been suggested as alternative molecular correlates of pathogenicity of human influenza viruses. I have read and accept the Wiley Online Library Terms and Conditions of Use
2017 Aug 3;7:338. doi: 10.3389/fcimb.2017.00338. If you do not receive an email within 10 minutes, your email address may not be registered, 2015 Jun;185(6):1528-36. doi: 10.1016/j.ajpath.2014.08.030.
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